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KMID : 0614620020390020128
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Korean Journal of Gastroenterology
2002 Volume.39 No. 2 p.128 ~ p.132
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A Case of Crohn's Disease Manifested by Generalized Edema and Severe Anemia
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김영호/Young Ho Kim
정진모/조광희/조상형/조현호/최대현/한철주/김진/정숙향/김유철/이진오/고재수*/Jin Mo Jung/Kwang Hee Cho/Sang Hyung Cho/Hyun Ho Cho/Dae Hyun Choi/Chul Ju Han/Jin Kim/Sook Hyang Jung/Yu Chul Kim/Jin Oh Lee/Jae Soo Koh*
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Abstract
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Iron deficiency anemia and hypoproteinemia occur commonly in patients with Crohn's disease. They invariably have
other clinical manifestations, principally abdominal pain, diarrhea and weight loss. However, severe anemia and hypoproteinemia as the sole presentation without any other clinical evidence to suggest Crohn's disease is extremely
uncommon and raises a diagnostic problem. A 31-year-old man presented with generalized edema and dyspnea on
exertion without any significant gastrointestinal symptoms. Hemoglobin level was 3.8 ｇ/㎗, and serum protein and
albumin levels were 3.5 ｇ/㎗ and 1.2 ｇ/㎗, respectively. Urinalysis finding was normal, and fecal clearance of α-1
antitrypsin increased markedly up to 873 ㎖/24 hr, suggesting severe protein loss through the gastrointestinal tract. A
CT scan and small bowel barium study revealed lesions in the j ejunum. Surgical resection corrected his problems, and
pathological examination of the specimen proved to be Crohn's disease.
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